bytimothyharvard

Referred to as stages or steps, there are 5 different phases or aspects of medical device product development. As there are significant regulations and requirements for all devices based on their intended use and their classification, it is essential to work with a medical device production company with an understanding of both the regulations as well as the production processes.

By choosing a company offering medical device product development as well as ISO 13485 certification, the original designer has the option to tap into the year of experience and expertise in the medical device development offered by the company. In most cases, the top manufacturers of injection molded parts also provide engineering services and full support for their customers throughout the process.

Stage 1: Research

[youtube]http://www.youtube.com/watch?v=Zz_dgjIjO2Y[/youtube]

It is essential for the inventor of the new medical device to fully research the market as well as the competition. Comparing what the proposed device will offer that is different or better than what is currently on the market is important. In addition, this is the first stage in the risk assessment of the device as well as to gain a clear understanding of all regulations and requirements.

Stage 2: Concept to Initial Prototype Development

This stage moves from concept through to the initial prototype. This will include the full scope of input from doctors and patients as well as the development of the drawings for the prototype and the analysis of that design. This is also where material selection and production methods are finalized and analyzed as to cost analysis.

Stage 3: Design and Development

This moves from prototype analysis and design to actual testing of the prototype along with verification and validation. In this phase, there is also a direct evaluation of the prototype by the end-users. It also includes the application for a patent and for regulatory approval.

Stage 4: Final Validation and Stage 5: Marketing Launch

These are the stages of medical device product development where the contract manufacturers are involved in ramping up to meet the anticipated market needs. At this time, approval has been received, and any clinical trials have been successfully completed.

Each stage of the process is critical for the company. Taking the time to select a medical device manufacturing company with the expertise to assist as needed in the development process has a very big impact on moving the process forward.

Monday, September 24, 2007

Marion Schaffer is running for the Green Party of Ontario in the Ontario provincial election, in the Oakville riding. Wikinews’ Nick Moreau interviewed her regarding her values, her experience, and her campaign.

Stay tuned for further interviews; every candidate from every party is eligible, and will be contacted. Expect interviews from Liberals, Progressive Conservatives, New Democratic Party members, Ontario Greens, as well as members from the Family Coalition, Freedom, Communist, Libertarian, and Confederation of Regions parties, as well as independents.

Tuesday, November 20, 2007

University of Michigan Wolverines head coach Lloyd Carr, who had coached the college football program for thirteen years, announced his retirement from the coaching profession, effective after the Wolverines’ bowl game.

“Yesterday was one of the most emotional days of my life,” Carr said at his press conference, referring to when he informed his team of his retirement. “I’ve cried more tears than I knew I had. I’ve never laughed so hard in my life. There’s so many memories. It was a wonderful day.”

During his tenure at Michigan, Carr won five Big Ten Conference championships and a national championship in 1997. He had a disappointing 1-6 record vs. Jim Tressel’s Ohio State Buckeyes, though his overall record vs. Ohio State was 6-7. Carr’s last victory over Ohio State came in 2003. He amassed a 121-40 overall record while at Michigan and ranks seventh among active coaches with a 75.2 winning percentage.

There has been a lot of speculation, even before Carr’s retirement, regarding who would become the next Michigan head coach. Current Louisiana State University head coach Les Miles is viewed as the top candidate to replace Carr.

Observers see Les Miles as the front-runner despite his recent comments. “I want to stay just where I’m at,” Miles said. “I don’t want to think about it. Don’t want to envision it. I want to go forward and prepare.”

Thursday, April 14, 2005

An exhausted Charles Kennedy returned to the election campaign to launch a twenty page Liberal Democrat manifesto targeted at disaffected Labour voters, promising a fairer tax system and withdrawal from Iraq.

Entitled The Real Alternative the manifesto pledges to reduce the lowest rate of income tax, but increase the rate on those earning over £100,000 to 50%. The party would also scrap the unpopular local council tax in favour of a new local income tax. The manifesto also promises to remove hidden “stealth taxes”.

Under this system the party claims the poorest 15 million (25%) of people in Britain would be better off, and the middle 50% would be paying no extra tax.

The manifesto promised to scrap the controversial university tuition fees, increase services for pensioners and add £100 a month to the state pension, and train 21,000 new primary school teachers and 10,000 new police. A Lib Dem government would make eye and dental checks free, and reduce the cost of prescription medicine.

The Liberal Democrats were the only one of the three largest parliamentary parties to have consistently voted against the Iraq war, and the manifesto has promised an exit strategy with a phased withdrawal of Britain’s 8,000 troops still in the country.

“We reject a foreign policy based on ‘my ally right or wrong’,” Kennedy said. “And we say that war should always be a last resort.”

Kennedy, who became a father on Tuesday, admitted he’d had little sleep before the manifesto launch, and stumbled while answering questions on the proposed tax system.

byAlma Abell

A dryer for the bathroom can make it much easier for people dry their hands and get in and out of the restroom quickly. However, finding hand dryers for sale may seem complicated until you understand more about the process. For example, you can choose to search for used ones, but you have no idea how often they’ve been serviced, what maintenance has been done, and how they were treated. It may be best to get a new machine for your business to ensure quality.

Speed And Performance

Dry times are an essential factor to consider because people are less likely to use them if they take more than a minute. Some hand dryers for sale can dry the hands in less than 10 seconds, making it faster and easier for the user. However, you should also consider performance because if it runs slowly, gets too hot, or doesn’t get hot enough, it can also cause people to dislike the dryer.

Noise Level

Another problem with older models is that they are extremely loud. It can sound like an airplane or helicopter taking off, which is unpleasant for the user, anyone else in the restroom, and those outside, as well. Choosing a quiet one will keep noise levels low and give everyone a more pleasant experience.

Hygiene

Touchless hand dryers for sale are always popular because they’re more hygienic. The user doesn’t have to touch the machine, but instead, puts their hands under the blower, and a sensor turns the machine on for them. It shuts off when the user removes their hands.

Energy Usage

With an automatic dryer, you also get better energy-efficiency. It doesn’t have a set dry time, which means it shuts off when hands are removed. They may also take less energy to start, as well, saving you money in the long run.

Friday, January 30, 2009

A court in London has sentenced a would-be suicide bomber to life imprisonment.

Nicky Reilly, 22, a Muslim convert with learning difficulties and Asperger syndrome, took the components for three bombs — glass bottles containing nails, caustic soda and kerosene — to the Giraffe restaurant in Exeter, south west England, in May 2008. One bottle exploded as Reilly attempted to assemble the device in the restaurant’s toilets, causing him facial and hand injuries. He was arrested outside the establishment.

Reilly entered a plea of guilty to attempted murder and engaging in preparation for terrorism when he appeared in court last year. The judge at the Central Criminal Court in London (known as the Old Bailey), Mr Justice Calvert-Smith, told him he would serve a minimum of 18 years, saying that it was “sheer luck or chance that [it] did not succeed in its objectives” and that “[t]he offence of attempted murder is aggravated by the fact that it was long-planned, that it had multiple intended victims and was intended to terrorise the population of this country”.

Reilly, also known as Mohammad Rashid Saeed Alim, was recruited via an online forum. He is believed to have a mental age of 10 and Devon and Cornwall Police said he had been “preyed on, radicalised and taken advantage of” by the members of the forum.

Wednesday, February 3, 2010

A French court Tuesday launched the trial of five men and a US airline over the Concorde disaster. 113 people were killed when the supersonic jet struck a hotel near Paris in 2000.

The prosecution case agrees with the facts set out in the final accident report, which, by international law, was written from an entirely different investigation and thus cannot be introduced in court. It alleges that improper maintenance of an American airliner and failure to detect design flaws with the Concorde were responsible for the Air France jet’s crash, to an extent that makes the six defendants guilty of involuntary manslaughter.

Both official investigations found that a Continental Airlines McDonnell Douglas DC-10 had taken off five minutes before Concorde with an improvised repair. A metal strip had been machined by mechanics instead of using a certified part. This strip dropped off the aircraft, leaving a 43cm (17in) piece of titanium on the runway.

Prosecutors and investigators concluded that as Concorde struck the part on takeoff a tyre burst and ripped apart, sending chunks of rubber flying. A large piece slammed into the underside of the wing hard enough to trigger a pressure wave that ruptured the fuel tank. Damaged wiring is believed to have been responsible for igniting this, creating a trailing fireball as the aircraft took off bound for New York.

Concorde’s pilots attempted to circle round for an emergency landing back at Charles de Gaulle Airport, but instead struck a hotel approximately three kilometres (two miles) from the airport. All 109 passengers and crew were on board, as well as four people in the hotel, were killed. The majority of victims were Germans heading to meet up with a cruise liner for a Caribbean holiday, the remainder of the 100 passengers were from Austria.

John Taylor, the Continental mechanic who is alleged to have built and fitted the nonstandard part, and his boss Stanley Ford, have been targeted for prosecution. Both individuals and their employer deny responsibility. Also charged are two members of the UK-French firm behind Concorde – Aérospatiale, who have since merged into Airbus parent EADS. Henri Perrier was head of testing for Concorde and the aircraft’s chief engineer was Jacques Herubel; both have been charged for a perceived failure to locate and rectify design flaws with Concorde. The former chief of civil aviation, Claude Frantzen, is facing charges on the same basis.

Each individual can be imprisoned for up to three years and fined up to €50,900 (US$71,000. Continental face a fine of up to €375,000 (US$520,000). The airline’s defence claims the part on the runway had no role to play in the accident. TV channel Canal+ previously suggested the investigations and prosecution were a coverup of more serious issues with Concorde.

Nothing was allowed to disturb Air France […] orders came from very high in the administration

The broadcast alleged Concorde erupted into flames long before getting as far down the runway as the strip. Continental’s lawyers say they can call 28 witnesses to give similar evidence and told the Le Parisien that they would seek a dismissal of the charges today. The case opened with judge Dominique Andreassier reading out every one of the 113 names of the deceased, followed by the charges against the six, in the court in Pontoise.

There are 80,000 pages of documents to be presented at trial, and 543 items are to be presented as evidence. The case is split into 90 volumes and is expected to take four months. The judge cautioned against losing touch with the human aspect of what is anticipated to be a very technical trial. The estimated cost is expected to be in excess of 3 million Euro (US$4.2 million).

The investigation found some contributory causes that can be linked to Air France. Four days before the crash an important tyre spacer was left off the Concorde by mechanics, and the plane was overloaded. The airport itself was also criticised for having cancelled a scheduled sweep of the runway. Air France lawyer Fernand Garnault, an aviation specialist, was adamant that Continental did play the main role in the accident; “[i]t is clear that a piece from a Continental plane fell on the runway. It is clear that the origin of the accident was this. This is my personal conviction and of course that of Air France.”

Few families are represented at the trial, because all the passengers struck a deal with Air France to accept compensation in exchange for waiving their right to take legal action, leaving only those killed in the hotel and the crew. However, French group Fenvac are representing the families, and spokesman Stephane Gicquel said that the families would be observing keenly, that “[t]his tragedy is part of their personal history and of their family history.”

Captain Christian Marty’s family’s lawyer, Roland Rappaport, said outside court today that, “[t]his accident should have been avoided. The weaknesses of the Concorde had been known for twenty years,” while Air France’s lawyers stated the inquiries had not located any evidence to suggest that Concorde had indeed encountered problems before reaching the metal debris.

Daniel Soulez Larivière, who represents Frantzen, said, “this accident was unforeseeable,” and the original investigations should have agreed. Concorde suffered a string of similar incidents in the 1970s including one in Washington that came close to triggering a fire. “They [the authorities] wanted to protect Concorde, the image of France that it projected. They should have stopped service then [1979],” said Olivier Metzner, representing Continental. The plane was not grounded until after the accident, although it returned to service before being retired in 2003.

Metzner told the court that former French air accident investigator Michel Bourgeois was to be a key witness. Bourgeois recently alleged that authorities were indeed hiding flaws with the airliner, saying “[n]othing was allowed to disturb Air France […] orders came from very high in the administration,” and that investigations into Concorde’s safety were shut down by the government.

Tuesday, January 19, 2010

A Scottish woman who set out before Christmas to purchase a turkey finally made it home on Monday, after being cut off by snow for a month. Kay Ure left the Lighthouse Keeper’s cottage on Cape Wrath, at the very northwest tip of Great Britain, in December. She was heading to Inverness on a shopping trip.

However on her return journey heavy snow and ice prevented her husband, John, from travelling the last 11 miles to pick her up. She was forced to wait a month in a friend’s caravan, before the weather improved and the couple could finally be reunited.

They were separated not just for Christmas and New Year, but also for Mr Ure’s 58th birthday. With no fresh supplies, he was reduced to celebrating with a tin of baked beans. He also ran out of coal, and had to feed the couple’s six springer spaniels on emergency army rations.

“It’s the first time we’ve been separated”, said Mr Ure in December. “We’ve been snowed in here for three weeks before, so we are well used to it and it’s quite nice to get a bit of peace and quiet.”

Share Trading: From \”Dependence\” to \”Self Reliance\”

by

MikeSmiths

With the advent of technology, the

share market

investors, who earlier used to call up their brokers and place stock trading instructions over the phone, now transact independently by making use of their respective

online trading accounts

, in the comfort of their homes and at the time they like, all at the click of the mouse. All one needs is a computer, a net connection and a subscription to a three in one online investing account.

Online trading is thus an internet based transaction activity that involves no direct involvement of the broker and thus reduced brokerage charges. The investor transacts himself and the buying and selling decision rests with him. Some online brokerages offer advice from live brokers and broker-assisted trades as part of their service, who help the investor fully understand the pros and cons before investing in a particular stock.

The investor has to register with a trusted online trading portal and enter into an agreement with the firm to trade in different securities following the terms and conditions laid down.

[youtube]http://www.youtube.com/watch?v=6sbnH7nYBgc[/youtube]

The online mode of investing largely eliminates all the major hassles of investing. Online brokers usually have good security measures, including automatic logouts and transmission encryption. The servers of the online trading portal are connected to the stock exchanges and designated banks. The order processing thus is done at correct timings. The trading platform also helps the investor in getting trading updates and in checking the current status of their orders. Another advantage is that the trading platform provides real time streaming quotes which enable quick decisions. Brokerage houses also provide qualitative research content (both fundamental as well as technical) in an investor friendly format on their websites, such that the clients can take informed decisions regarding investing. One can invest anytime and from anywhere as per their time and convenience (yes, even at night)!

In India, the major financial products and services of the online trading are:

— Equities

Mutual funds

— Derivatives

— Insurance (Life and Non Life)

— Loans

— Fixed deposits and bonds

— Share trading

— Commodities trading

— Tax services

— Portfolio management and financial planning

In the course of his dealings, an investor should always ensure that sufficient funds and securities are available in his account and that he is regular in payment of margins so as to avoid the blocking of his account.

Kotak Securities is one of India’s leading

stock broking firm

offering stock trading, mutual fund and IPO investing service’s along with a research division specializing in Sectoral research and Company Specific

Equity Research

.Express your views on their Facebook Page and Twitter Handle (@KotakSecurities) or you can also browse through their various videos on YouTube and Slide Share.

Article Source:

ArticleRich.com

Sunday, November 9, 2008

Voters in California, Florida and Arizona voted on Tuesday to ban gay marriage, bringing about a victory for conservatives on a day which did not bring many conservative wins.

Meanwhile, voters in Colorado, South Dakota and California voted on measures which would have restricted abortion in those states. In Massachusetts and Michigan, voters passed measures that loosen marijuana laws. Finally, in the state of Washington a measure was passed that allows physician-assisted suicide.

The California ballot measure, Proposition 8, overturns the recent June ruling by the California State Supreme Court in the case In re Marriage Cases which reversed a 1977 statute passed by the California State Legislature and a 2000 ballot measure, Proposition 22, which also banned same-sex marriage by defining marriage as between a man and a woman. The wording of Proposition 8 is identical to Proposition 22. It was noted that many of the African-Americans and Latinos who cast their votes for Obama, also voted for the measure. The measure passed at 52% to 48%.

Lesbian comedian Ellen DeGeneres noted, “This morning, when it was clear that Proposition 8 had passed in California, I can’t explain the feeling I had. I was saddened beyond belief. Here we just had a giant step toward equality and then on the very next day, we took a giant step away.”

Okay, so I am taking that to mean I do not have to pay my state taxes because I am not a full citizen.

Singer Melissa Etheridge, who is also a lesbian, stated that she would no longer pay taxes due to the passing of Proposition 8, announcing in a blog post, “Okay, so I am taking that to mean I do not have to pay my state taxes because I am not a full citizen.”

Also in California, voters rejected a measure which would require parental notification for a minor to receive an abortion. The measure was rejected with the same percentage as Proposition 8, 52% to 48%. Meanwhile in Colorado, voters rejected a measure that would define life as beginning at conception. While the measure did not specifically mention abortion it would have required legislators and courts to confront legal rights for fetuses – effectively preventing abortion. The measure was defeated in a wide margin, 73% to 27%

In South Dakota, voters also defeated an anti-abortion measure which would have outlawed abortion in all cases except in the case of rape, incest or if the mother’s health was in serious question. If passed, the law would most likely have been challenged as unconstitutional.

In Michigan, voters approved a measure which legalizes medical marijuana. Meanwhile, in Massachusetts, voters approved a ballot question that decriminalizes possession of small amounts of marijuana in which the possession of an ounce or less would be punishable by a $100 fine. The measure will also require minors under the age 18 to participate in and complete a drug awareness program and do community service. Failure to do so, would net the minor a $1,000 fine.

“Tonight’s results represent a sea change. Voters have spectacularly rejected eight years of the most intense government war on marijuana since the days of ‘Reefer Madness,'” said Rob Kampia, executive director of the Marijuana Policy Project. “The people were ahead of the politicians on this issue; they recognize and want a more sensible approach to our marijuana policy,” said Whitney Taylor, the chair of Committee for Sensible Marijuana Policy, which backed the Massachusetts proposition.

Also, in Massachusetts, voters overwhelmingly, in every single Massachusetts city and town, rejected a ballot measure which would have eliminated the state income tax by 2010, the ballot measure was sponsored by the Committee for Small Government, which is headed up by two libertarians, Michael Cloud, a Libertarian Party candidate for U.S. Senate in 2002 and Carla Howell, Libertarian Party candidate for governor in the 2002 Massachusetts gubernatorial election.

The last time the income tax elimination measure was on the ballot was in 2002, where it was defeated, narrowly by 45.3%. This stunned supporters of the income tax, who mounted a fierce campaign against the measure this time warning Massachusetts residents that repealing the income tax would have drastic effects on the state’s finances, leading to cuts in services, education and local aid.

Finally, voters passed a question which bans dog racing in Massachusetts, which will lead to the closure of Massachusetts’ two greyhound racing tracks, Raynham-Taunton Greyhound Park and Wonderland Greyhound Park.

The campaign against dog racing was headed up by the Committee to Protect Dogs and endorsed by GREY2K USA and the American Society for the Prevention of Cruelty to Animals along with other animal protection organizations who claimed that dog racing was inhumane as the dogs were stuffed into cramped cages and endured injuries. The measure was opposed by the park owners including George Carney who owns the Rayham-Taunton park and Charles Sarkis, a restaurateur who owns Wonderland.

“We did it. We did it for the dogs,” said Carey Thiel, executive director of GREY2K USA. “For 75 years, greyhounds in our state have endured terrible confinement and suffered serious injuries. We’re better than that,” Thiel added.

One campaign supporter, Sandy Bigelow noted, “It means everything. We’ve worked so hard for the dogs and they heard us. It feels so good. Oh, God, it feels so good.”

George Carney said of the results, “It’s not a very pleasant thing right now. Some of these people have been here 40 years. Here’s a company that did nothing wrong, paid their federal taxes on time, paid the town on time. The town is going to be a severe loser, and a lot of people here dedicated their life to the company.”

We did it. We did it for the dogs.

Both sides used emotionally-charged advertisements, the anti-racing side showing “sad-eyed greyhounds,” while the pro-racing side highlighted the workers who would be out of work when the tracks close.

Both measures must now come before the Massachusetts Governor’s Council for approval.

A ballot initiative approved by voters in the north-western state of Washington will make it the second state to permit physician-assisted suicide. Initiative 1000 follows the ten-year-old example of the Death With Dignity Act of neighboring Oregon, and will allow physicians to prescribe a lethal dose of medication for a terminally ill patient to administer themselves. It was approved by a margin of 16%, and the ‘Yes’ campaign outspent the ‘No’ campaign by more than three-to-one. The law comes into effect in 2009.